Nasal polyps

Common Name(s)

Nasal polyps

Nasal polyps are sac-like growths in the nasal passages, which is the area of the nose that extends from the nostrils up into the nose. These growths are not cancerous or harmful, but they may lead to problems such as if they become enlarged or if they obstruct the nasal passage. Small polyps may cause no symptoms at all, while large polyps may block drainage and lead to infection. Anyone can have nasal polyps, but they are more common in men and in people over age 40. Children who have nasal polyps should be screened for cystic fibrosis, as nasal polyps are a common finding in this disease. Risk factors for nasal polyps are asthma, sinus infections, presence of a foreign object in the nose, and allergic rhinitis (runny nose caused by allergies).

Symptoms of nasal polyps include nasal congestion, a runny nose, snoring, pain in the upper teeth or face, sneezing, loss of smell (anosmia), reduced sense of smell (hyposmia), itching around the eyes, headache, or infections. Nasal polyps can be diagnosed with a nasal endoscope, which is a lighted tube that is used to look up the nose. Treatment can include medications, such as nasal sprays and allergy medications, or surgery. If you have nasal polyps, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasal polyps" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nasal polyps" returned 157 free, full-text research articles on human participants. First 3 results:

A disintegrin and metalloprotease 10-containing exosomes derived from nasal polyps promote angiogenesis and vascular permeability.
 

Author(s): Wei Zhang, Jie Zhang, Lei Cheng, Haosheng Ni, Bo You, Ying Shan, Lili Bao, Di Wu, Ting Zhang, Huijun Yue, Jing Chen

Journal: Mol Med Rep. 2018 Apr;17(4):5921-5927.

 

Abnormal angiogenesis and vascular permeability is important for the formation of nasal polyps (NPs). Increasing evidence has indicated that exosomes serve a vital role in modulating angiogenesis and vascular permeability. A disintegrin and metalloprotease 10 (ADAM10), an important ...

Last Updated: 31 Dec 1969

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How often is sinus surgery performed for chronic rhinosinusitis with versus without nasal polyps?
 

Author(s): Elisabeth H Ference, Jeffrey D Suh, Bruce K Tan, Stephanie Shintani Smith

Journal: Am J Rhinol Allergy. 2018 Jan;32(1):34-39.

 

There currently are no data on the relative frequency of endoscopic sinus surgeries (ESS) performed for chronic rhinosinusitis with nasal polyposis (CRSwNP) versus chronic rhinosinusitis without nasal polyposis (CRSsNP) in the United States.

Last Updated: 31 Dec 1969

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A family-based genome-wide association study of chronic rhinosinusitis with nasal polyps implicates several genes in the disease pathogenesis.
 

Author(s): Anton Bohman, Julius Juodakis, Martin Oscarsson, Jonas Bacelis, Mats Bende, Åsa Torinsson Naluai

Journal:

 

The pathogenesis of chronic rhinosinusitis with nasal polyps is largely unknown. Previous studies have given valuable information about genetic variants associated with this disease but much is still unexplained. Our goal was to identify genetic markers and genes associated with susceptibility ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nasal polyps" returned 12 free, full-text review articles on human participants. First 3 results:

Polymorphisms in chronic rhinosinusitis with nasal polyps - a systematic review.
 

Author(s): Vanessa Ramos Pires Dinarte, Anemari Ramos Dinarte Dos Santos, Luiza Ferreira de Araújo, Mariah Guieiro Alves Dos Reis, Edwin Tamashiro, Fabiana Cardoso Pereira Valera, Wilson Araújo da Silva Júnior, Wilma Terezinha Anselmo-Lima

Journal: Braz J Otorhinolaryngol. ;83(6):705-711.

 

Chronic rhinosinusitis with nasal polyps is a multifactorial disease with a complex pathophysiology involving multiple genetic and environmental factors.

Last Updated: 31 Dec 1969

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Chronic Rhinosinusitis without Nasal Polyps.
 

Author(s): Seong Ho Cho, Dae Woo Kim, Philippe Gevaert

Journal: J Allergy Clin Immunol Pract. ;4(4):575-82.

 

Chronic rhinosinusitis without nasal polyps (CRSsNP) is more prevalent than chronic rhinosinusitis with nasal polyps (CRSwNP). Certain diseases predispose to whereas others are associated with CRSsNP. Predisposing diseases include allergic and nonallergic upper and lower airway diseases, ...

Last Updated: 31 Dec 1969

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Chronic Rhinosinusitis with Nasal Polyps.
 

Author(s): Whitney W Stevens, Robert P Schleimer, Robert C Kern

Journal: J Allergy Clin Immunol Pract. ;4(4):565-72.

 

Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed by the presence of both subjective and objective evidence of chronic sinonasal inflammation. Symptoms include anterior or posterior rhinorrhea, nasal congestion, hyposmia, and/or facial pressure ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Activation of Hippo Pathway in Nasal Polyps
 

Status: Recruiting

Condition Summary: Nasal Polyps

 

Last Updated: 10 Sep 2018

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Effect of Benralizumab in Patients With Severe Nasal Polyps
 

Status: Recruiting

Condition Summary: Nasal Polyps

 

Last Updated: 10 Aug 2018

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An Extension Study of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps
 

Status: Recruiting

Condition Summary: Nasal Polyps; Chronic Rhinosinusitis

 

Last Updated: 7 Sep 2018

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