Necrotizing fasciitis

Common Name(s)

Necrotizing fasciitis

Necrotizing fasciitis is a serious bacterial infection of the skin, subcutaneous tissue (tissue just beneath the skin) and fascia. The infection can be sudden and fast-spreading. The bacteria involved enters the body through an external injury and attacks the surrounding tissues, eventually causing them to die. Early signs include flu-like symptoms and redness or pain around the infection site, followed by very high fever, severe pain, swelling and blistering. If the infection is not treated promptly, it may cause multiple organ failure and death. Treatment typically includes intravenous antibiotics; surgery to remove infected and dead tissue; hyperbaric oxygen therapy; and intravenous immune globulin therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Necrotizing fasciitis" returned 225 free, full-text research articles on human participants. First 3 results:

Signs, symptoms and diagnosis of necrotizing fasciitis experienced by survivors and family: a qualitative Nordic multi-center study.
 

Author(s): Annette Erichsen Andersson, Ingrid Egerod, Vibeke E Knudsen, Ann-Mari Fagerdahl

Journal:

 

Necrotizing soft tissue infection is the most serious of all soft tissue infections. The patient's life is dependent on prompt diagnosis and aggressive treatment. Diagnostic delays are related to increased morbidity and mortality, and the risk of under- or missed diagnosis is high ...

Last Updated: 31 Dec 1969

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[Necrotizing fasciitis caused by a Garengeot's hernia. Case report].
 

Author(s): Eduardo Briceño, Rocío Jara

Journal: Rev Med Chil. 2018 May;146(5):660-664.

 

Garengeot's hernia corresponds to the presence of the appendix within a femoral hernia, associated or not with acute appendicitis. The diagnosis of this uncommon situation is usually done during surgery. Furthermore, the clinical presentation as necrotizing fasciitis is a rare condition. ...

Last Updated: 31 Dec 1969

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Bilateral periorbital necrotizing fasciitis: case report.
 

Author(s): Fabio Henrique Luiz Leonardo, Mariana Anabuki, Allan Christian Pieroni Gonçalves

Journal: Arq Bras Oftalmol. 2018 06;81(3):239-241.

 

Necrotizing fasciitis is a severe infection of the subcutaneous tissue characterized by necrosis of the superficial fascia and overlying skin and is usually associated with previous trauma and comorbidities. Periorbital necrotizing fasciitis is rare and commonly causes visual loss ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Necrotizing fasciitis" returned 20 free, full-text review articles on human participants. First 3 results:

Negative Pressure Wound Therapy for a Giant Wound Secondary to Malignancy-induced Necrotizing Fasciitis: Case Report and Review of the Literature.
 

Author(s): Jiayi Hu, Serge Goekjian, Nicolas Stone, Alexandra Nelson, Michael James Cooper

Journal: Wounds. 2017 Aug;29(8):E55-E60.

 

Necrotizing fasciitis (NF) is a life-threatening condition in which rapid diagnosis, debridement of nonviable tissue, and broad-spectrum antibiotics are critical to effective treatment. The debridement required can be extensive, resulting in large wounds that can sometimes be covered ...

Last Updated: 31 Dec 1969

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Necrotizing fasciitis-A catastrophic complication following routine tibia fracture surgery: A case report and literature review.
 

Author(s): Shuai Shang, Ruipeng Zhang, Zhiyong Hou

Journal: Medicine (Baltimore). 2017 Jun;96(23):e6908.

 

Necrotizing fasciitis (NF) is defined as a rare, life-threatening, rapidly spreading soft tissue infection resulting from a polymicrobial origin, with a predominance of anaerobic organisms that presents with necrosis of the muscle, fascia, and surrounding soft tissue.

Last Updated: 31 Dec 1969

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Aeromonas sobria necrotizing fasciitis and sepsis in an immunocompromised patient: a case report and review of the literature.
 

Author(s): Savino Spadaro, Angela Berselli, Elisabetta Marangoni, Anna Romanello, Maria Vittoria Colamussi, Riccardo Ragazzi, Silvia Zardi, Carlo Alberto Volta

Journal:

 

Aeromonas veronii biovar sobria is a rare cause of bacteremia, with several studies indicating that this isolate may be of particular clinical significance since it is enterotoxin producing. A wide spectrum of infections has been associated with Aeromonas species in developing countries ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Severe Soft Tissue Infections: Perspectives of Patients and Significant Others
 

Status: Recruiting

Condition Summary: Necrotizing Fasciitis

 

Last Updated: 13 Aug 2018

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Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infections; Necrotizing Fasciitis; Fournier's Gangrene

 

Last Updated: 16 Nov 2018

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Prognosis and Treatment of Necrotizing Soft Tissue Infections: A Prospective Cohort Study
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infection; Necrotizing Fascitis; Gas Gangrene; Fournier Gangrene

 

Last Updated: 6 May 2017

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