Necrotizing fasciitis

Common Name(s)

Necrotizing fasciitis

Necrotizing fasciitis is a serious bacterial infection of the skin, subcutaneous tissue (tissue just beneath the skin) and fascia. The infection can be sudden and fast-spreading. The bacteria involved enters the body through an external injury and attacks the surrounding tissues, eventually causing them to die. Early signs include flu-like symptoms and redness or pain around the infection site, followed by very high fever, severe pain, swelling and blistering. If the infection is not treated promptly, it may cause multiple organ failure and death. Treatment typically includes intravenous antibiotics; surgery to remove infected and dead tissue; hyperbaric oxygen therapy; and intravenous immune globulin therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Necrotizing fasciitis" returned 208 free, full-text research articles on human participants. First 3 results:

Acute appendicitis complicated with necrotizing fasciitis in a patient with adult-onset Still's disease: A case report.
 

Author(s): Zheng-Hao Huang, Yu-Chen Chiu, Li-Lu Ho, Hsiu-Lung Fan, Chun-Chi Lu

Journal: Medicine (Baltimore). 2018 Feb;97(5):e9794.

 

Adult-onset Still disease (AOSD) is a rare systemic inflammatory disease of unknown etiology characterized by evanescent salmon-pink rash, spiking fever, arthralgia/ arthritis, and lymphadenopathy. AOSD sometimes was fatal when it is complicated by macrophage activation syndrome (MAS) ...

Last Updated: 31 Dec 1969

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Alcohol use disorder increases the risk of necrotizing fasciitis: A nationwide retrospective cohort study.
 

Author(s): Yong-Cheng Yii, Vivian Chia-Rong Hsieh, Cheng-Li Lin, Yu-Chiao Wang, Wei-Kung Chen

Journal: Medicine (Baltimore). 2017 Aug;96(32):e7509.

 

This nationwide retrospective cohort study determined the association between alcohol use disorder (AUD) and the risk of necrotizing fasciitis (NF).This study used health insurance claims data of 52,212 in-patients with AUD and 208,848 controls randomly frequency-matched by age and ...

Last Updated: 31 Dec 1969

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Risk Factors For Necrotizing Fasciitis And Its Outcome At A Tertiary Care Centre.
 

Author(s): Yogendra Gupta, Manisha Chhetry, Kamal Raj Pathak, Ranjib Kumar Jha, Nischal Ghimire, Bibhuti Nath Mishra, Navin Kumar Karn, Ganesh Kumar Singh, Jatindra Nath Bhagabati

Journal: J Ayub Med Coll Abbottabad. ;28(4):680-682.

 

Necrotizing fasciitis (NF) is a serious and potentially fatal condition where there is rapid progression of inflammation of skin, subcutaneous tissue, and superficial fascia and can be mono-microbial or poly-microbial. The disease is rapidly progressive in nature and if not promptly ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Necrotizing fasciitis" returned 19 free, full-text review articles on human participants. First 3 results:

Necrotizing fasciitis-A catastrophic complication following routine tibia fracture surgery: A case report and literature review.
 

Author(s): Shuai Shang, Ruipeng Zhang, Zhiyong Hou

Journal: Medicine (Baltimore). 2017 Jun;96(23):e6908.

 

Necrotizing fasciitis (NF) is defined as a rare, life-threatening, rapidly spreading soft tissue infection resulting from a polymicrobial origin, with a predominance of anaerobic organisms that presents with necrosis of the muscle, fascia, and surrounding soft tissue.

Last Updated: 31 Dec 1969

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Aeromonas sobria necrotizing fasciitis and sepsis in an immunocompromised patient: a case report and review of the literature.
 

Author(s): Savino Spadaro, Angela Berselli, Elisabetta Marangoni, Anna Romanello, Maria Vittoria Colamussi, Riccardo Ragazzi, Silvia Zardi, Carlo Alberto Volta

Journal:

 

Aeromonas veronii biovar sobria is a rare cause of bacteremia, with several studies indicating that this isolate may be of particular clinical significance since it is enterotoxin producing. A wide spectrum of infections has been associated with Aeromonas species in developing countries ...

Last Updated: 31 Dec 1969

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Cervical necrotizing fasciitis: report of 6 cases and review of literature.
 

Author(s): P Cruz Toro, À Callejo Castillo, J Tornero Saltó, X González Compta, A Farré, M Maños

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Dec;131(6):357-359.

 

Necrotizing fasciitis in the cervical region is a rare entity, characterized by a fulminant infection that causes extensive necrosis of the subcutaneous tissue and fascial planes, with high mortality and morbidity rates. The origin is generally odontogenic or pharyngeal, involving ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Factors Associated With Complications of Cervical Necrotizing Fasciitis
 

Status: Recruiting

Condition Summary: Cervical Necrotizing Fasciitis

 

Last Updated: 25 Jul 2016

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Severe Soft Tissue Infections: Perspectives of Patients and Significant Others
 

Status: Recruiting

Condition Summary: Necrotizing Fasciitis

 

Last Updated: 11 Aug 2017

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Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).
 

Status: Recruiting

Condition Summary: Soft Tissue Infections; Necrotizing Fasciitis; Necrotizing Soft Tissue Infections

 

Last Updated: 16 Aug 2017

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