Neutropenia

Common Name(s)

Neutropenia

Neutropenia is a disorder in which individuals have an abnormally low count of neutrophils, a type of white blood cell that helps fight off infections. The low count can be caused by cancer, viral infections, autoimmune disorders or drugs that damage the function of bone marrow or neutrophil cells. The lower the neutrophil count, the more vulnerable an individual is to infection or sickness. Common symptoms of neutropenia include fevers and frequent infections, which can result in mouth ulcers, diarrhea, a burning sensation when urinating, unusual redness, pain, or a sore throat.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neutropenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neutropenia" returned 972 free, full-text research articles on human participants. First 3 results:

Long-Term Effects of G-CSF Therapy in Cyclic Neutropenia.
 

Author(s): David C Dale, AudreyAnna Bolyard, Tracy Marrero, Vahagn Makaryan, MaryAnn Bonilla, Daniel C Link, Peter Newburger, Akiko Shimamura, Laurence A Boxer, Charles Spiekerman

Journal: N. Engl. J. Med.. 2017 12;377(23):2290-2292.

 

Last Updated: 31 Dec 1969

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[Nasal phaeohyphomycosis by Curvularia spicifera in pediatric patient with neutropenia and acute myeloid leukemia].
 

Author(s): Constanza Bay, Tamara González, Gonzalo Munoz, Paulette Legarraga, Cecilia Vizcaya, Katia Abarca

Journal: Rev Chilena Infectol. 2017 Jun;34(3):280-286.

 

There are very few reports of pediatric patients with infections by dematiaceous filamentous fungi. In this publication we report a case of invasive fungal infection of the nasal septum by Curvularia spicifera in a pediatric patient with acute myeloid leukemia. The patient presented ...

Last Updated: 31 Dec 1969

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Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features.
 

Author(s): Raphael Carapito, Martina Konantz, Catherine Paillard, Zhichao Miao, Angélique Pichot, Magalie S Leduc, Yaping Yang, Katie L Bergstrom, Donald H Mahoney, Deborah L Shardy, Ghada Alsaleh, Lydie Naegely, Aline Kolmer, Nicodème Paul, Antoine Hanauer, Véronique Rolli, Joëlle S Müller, Elisa Alghisi, Loïc Sauteur, Cécile Macquin, Aurore Morlon, Consuelo Sebastia Sancho, Patrizia Amati-Bonneau, Vincent Procaccio, Anne-Laure Mosca-Boidron, Nathalie Marle, Naël Osmani, Olivier Lefebvre, Jacky G Goetz, Sule Unal, Nurten A Akarsu, Mirjana Radosavljevic, Marie-Pierre Chenard, Fanny Rialland, Audrey Grain, Marie-Christine Béné, Marion Eveillard, Marie Vincent, Julien Guy, Laurence Faivre, Christel Thauvin-Robinet, Julien Thevenon, Kasiani Myers, Mark D Fleming, Akiko Shimamura, Elodie Bottollier-Lemallaz, Eric Westhof, Claudia Lengerke, Bertrand Isidor, Seiamak Bahram

Journal: J. Clin. Invest.. 2017 Nov;127(11):4090-4103.

 

Shwachman-Diamond syndrome (SDS) (OMIM #260400) is a rare inherited bone marrow failure syndrome (IBMFS) that is primarily characterized by neutropenia and exocrine pancreatic insufficiency. Seventy-five to ninety percent of patients have compound heterozygous loss-of-function mutations ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neutropenia" returned 88 free, full-text review articles on human participants. First 3 results:

[Advances in research on childhood neutropenia].
 

Author(s): Jian-Hua Feng, Yan Qian

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2017 Apr;19(4):484-489.

 

Neutrophils, an important type of human immune cells, are involved in host defense against infections. Neutropenia refers to a group of diseases manifesting as a reduction in the absolute value of mature neutrophils and is often accompanied by an increased risk of bacterial infection. ...

Last Updated: 31 Dec 1969

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An update on the diagnosis and treatment of chronic idiopathic neutropenia.
 

Author(s): David C Dale, Audrey A Bolyard

Journal: Curr. Opin. Hematol.. 2017 Jan;24(1):46-53.

 

Neutropenia lasting for at least for 3 months and not attributable to drugs or a specific genetic, infectious, inflammatory, autoimmune or malignant cause is called chronic idiopathic neutropenia (CIN). CIN and autoimmune neutropenia (AIN) are very similar and overlapping conditions. ...

Last Updated: 31 Dec 1969

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Neutropenia as an Adverse Event following Vaccination: Results from Randomized Clinical Trials in Healthy Adults and Systematic Review.
 

Author(s): Vincent Muturi-Kioi, David Lewis, Odile Launay, Geert Leroux-Roels, Alessandra Anemona, Pierre Loulergue, Caroline L Bodinham, Annelies Aerssens, Nicola Groth, Allan Saul, Audino Podda

Journal:

 

In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported. It is therefore important to evaluate how these trials should be planned not to miss potentially important safety ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Management of Severe Chemotherapy-induced Neutropenia in Advanced Breast Cancer
 

Status: Recruiting

Condition Summary: Febrile Neutropenia

 

Last Updated: 19 Oct 2017

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Last Updated: 26 Dec 2017

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