Serum level of adiponectin 1 describes the amount of the protein, adiponectin, in the body’s blood which comes from fat cells in our body (adipocytes). Adipose tissue is the loose connective fatty tissue under the skin. However, obese individuals tend to have lower levels of adiponectin secretion despite having higher body fat percentages. The lack of adiponectin has negative consequences on metabolic activities within the body. For example, adiponectin influences how the body responds to insulin, which is required for the body to control the amount of sugar within the bloodstream.
Low levels of adiponectin have been linked to inflammation, lipid abnormalities, insulin resistance, and increased risk of diabetes, nonalcoholic fatty liver disease (NAFLD), coronary heart disease, and cancer. Studies show that levels of adiponectin secretion may be inherited from parents, but the exact mechanism of heritability is unknown.
There are no definitive symptoms to identify low levels of adiponectin. However, symptoms related to diabetes, obesity, low levels of cholesterol, and high levels of triglycerides can indicate abnormalities in adiponectin levels. Changes in metabolic activity are a strong indicator of low adiponectin levels. Clinical measurement of adiponectin levels is not common in clinical practice, but methods of measuring adiponectin levels do exist. Consult with your doctor for more information. Adiponectin levels increase with reduced weight. Therefore, exercise and adopting a healthier lifestyle can help reduce symptoms. Prescription medications also exist to help increase adiponectin levels.
If you or a family member has been diagnosed with abnormal adiponectin levels, talk with your doctor about the most current treatment options. Support groups may also provide resources for support and information.
Description Last Updated: Aug 15, 2018