Yaws is a tropical disease caused by a form of bacteria known as treponemes that affects the skin, bone, and cartilage. This disease mainly affects children under the age of 15, and is found primarily in poor communities in warm, humid, and tropical forest areas of Africa, Asia, Latin America, and the Pacific. Yaws is transmitted from person to person through direct non-sexual contact with the fluids from the lesion of an infected person. Signs and symptoms include an early infectious stage and a late non-infectious stage. During the early infectious stage, an initial clear, circular swelling of the skin will develop at the site of entry. Other signs in the early stage are thinkening and darkening of the palms of the hands and soles of the feet. Bone pain and bone lesions may also appear in the early stage. Late Yaws symptoms appear five years after the initial infection and include disfigurement of the nose and bones and thickening of the palms of the hand and the soles of the feet. Humans are the only reservoir of Yaws.